$69.99
ARA-290 is a synthetic peptide derived from erythropoietin, engineered for selective receptor interaction without erythropoietic activity. It is classified as a non-hematopoietic EPO mimetic and is studied for its engagement with innate repair receptor pathways. Supplied at high purity, it is intended strictly for laboratory-based research applications.
ARA-290, also known as cibinetide, is an 11-amino acid peptide derived from the structural features of Erythropoietin. It is specifically designed to interact with the innate repair receptor, a heteromeric receptor complex distinct from the classical erythropoietin receptor responsible for hematopoiesis. This selectivity enables researchers to study tissue-protective signaling pathways without influencing red blood cell production, making it a valuable compound in mechanistic research.
ARA-290 has been investigated in experimental models focused on neurological signaling and cellular response mechanisms. Research explores its interaction with pathways involved in neuroinflammation and cellular stress. It has been used in studies examining signaling cascades such as JAK2/STAT and NF-κB, which play roles in cellular communication and response to environmental stimuli.
Laboratory studies also evaluate its ability to interact with neural cell types, including neurons and glial cells. Observations include modulation of signaling processes associated with microglial activation and cellular communication within neural environments.
In controlled research settings, ARA-290 is studied for its selective engagement of the innate repair receptor and its downstream effects on immune signaling pathways. Experimental work has focused on its influence on cytokine signaling and cellular responses associated with inflammatory processes.
Researchers have also explored its role in macrophage activity and immune cell signaling dynamics. These studies aim to understand how receptor-specific activation can alter signaling pathways involved in immune system responses without engaging hematopoietic mechanisms.
ARA-290 is widely examined in models studying cellular stress and repair signaling. Research includes its interaction with pathways involved in apoptosis regulation, mitochondrial activity, and oxidative stress response. These mechanisms are critical in understanding how cells respond to environmental stressors and maintain structural integrity.
Its defined peptide structure and receptor selectivity make ARA-290 a useful tool for investigating signaling pathways associated with cellular homeostasis and adaptive responses in various experimental systems.
This product is meant only for research use. It is made for lab testing and in vitro experiments (outside a living body), not for use in people or animals. All information on this website is for learning purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. It should only be used by trained professionals in a proper lab setting. This product is not a medicine, food, or cosmetic, and must not be sold or used as one.
